JOHN HOPKINS HASTANESİ’NDEN MI ??

 

INTERNETTEN ZARARLI VE UYDURMA BIR HABER VE JOHN HOPKINS’DEN YANIT

“John Hopkins Hospital. Nihayet itiraf etmişler, kemoterapi,radyoterapi ve cerrahi müdahale kanseri yenemiyor…”

Date: Mon, 24 Sep 2012
JOHN HOPKINS HASTANESİ’NDEN
1) Herkesin vücudunda kanser hücreleri vardır. Bu kanser hücreleri birkaç milyara kadar çoğalmadıkça standart testlerde görülmezler. Doktorlar kanser hastalarına tedaviden sonra vücutlarında artık kanser hücresi kalmadığını söyledikleri zaman, bu yalnızca kanser hücrelerinin testlerle saptanamayacak düzeyde olduğu anlamına gelir.
2) Bir kişinin hayatı boyunca 6 ile 10 kez kanser hücreleri oluşabilir.
3) Kişinin bağışıklık sistemi güçlü olduğu zaman kanser hücreleri yok edilir ve çoğalarak tümör oluşturmalarına engel olunur.
4) Bir kişide kanser olması, o kişide çoklu beslenme eksikliği olduğuna işaret eder. Bunlar genetik, çevresel, beslenme ve yaşam tarzı faktörlerine bağlı olabilir.
5) Çoklu beslenme eksiklini yenebilmek için diyeti değiştirmek ve ek takviye almak bağışıklık sistemini güçlendirir.
6) Kemoterapi hem hızlı çoğalan kanser hücrelerini, hem de kemik iliğinde, sindirim sisteminde v.s..’deki hızlı büyüyen sağlıklı hücreleri yok eder ve karaciğer, böbrekler, kalp, akciğerler v.s.’de organ tahribatına yol açar.
7) Radyasyon kanser hücrelerini yok ederken; sağlıklı hücre, doku ve organları da yakar, yaralar ve zarar verir.
8) Kemoterapi ve radyasyon başlangıçta tümörün küçülmesine yol açar. Kemoterapi ve radyasyon tedavisinin uzaması tümörün daha fazla yok olmasına yol açmaz.
9) Kemoterapi ve radyasyondan dolayı vücut çok fazla toksin yüklenmesine maruz kalınca, bağışıklık sistemi ya tehlikeye düşer, ya da yıkılır; dolayısıyla kişi çeşitli enfeksiyonlara ve komplikasyonlara yenik düşer.
10) Kemoterapi ve radyasyon kanser hücrelerinde mutasyona neden olabilir ve dirençlerinin artarak yok edilmelerini zorlaştırabilir. Cerrahi işlem de kanser hücrelerinin başka taraflara atlamasına neden olabilir.
11) Kanser hücreleri ile savaşmakta etkili bir yöntem ise onları çoğalmak için ihtiyaçları olan gıdalardan yoksun ve aç bırakmaktır.
KANSER HÜCRELERİ AŞAĞIDAKİLERLE BESLENİRLER:
a- Şeker kanser besleyicidir. Şekeri kesilerek kanser hücrelerinin önemli bir gıdası kesilmiş olur. NutraSweet, Equal, Spoonful v.s. gibi tatlandırıcılar zararlı olan Aspartam ile yapılırlar. Daha iyi bir tatlandırıcı Manuka balı veya molastır, ama az miktarda alınmalıdırlar. Sofra tuzunda beyazlatıcı olarak kimyasallar bulunmaktadır. Daha iyi bir seçenek Bragg’in aminosu veya deniz tuzudur.
b- Süt vücudun, özellikle sindirim sisteminde, mukus üretmesine neden olur.. Kanser mukusla beslenir. Süt yerine tatlandırılmamış soya sütü tüketilerek kanser hücreleri aç bırakılabilir.
c- Kanser hücreleri asit ortamda gelişirler. Et temelli diyet asittir ve sığır eti veya domuz eti yerine bol balık ve az tavuk eti yemek en iyisidir. Ette, özellikle kanserli kişilere zararı olan, canlı hayvan antibiyotikleri, büyüme hormonları ve parazitleri bulunur.
d- %80 taze sebze ve meyve suyu, kepekli tahıllar, tohumlar, nohutgiller ve biraz meyveden oluşan bir diyet vücudu bazik (alkali) ortamda tutar.. %20 de fasulye içeren pişmiş gıdalardan oluşabilir. Taze sebze suları kolayca emilip 15 dakika içinde hücre düzeyine ulaşabilen ve sağlıklı hücreleri besleyen ve çoğalmalarını hızlandıran canlı enzimler içerirler. Sağlıklı hücre üretimi için gerekli olan canlı enzimlerin sağlanması amacıyla, taze sebze (sebzelerin çoğunluğu ve fasulye filizi) yiyin veya suyunu için ve günde 2-3 kez çiğ sebze yiyin. Enzimler 40o C’de yok olurlar.
e- Yüksek kafein içerikli kahve, çay ve çikolatadan uzak durun. Yeşil çay daha iyi bir seçenektir ve kanserle savaşan özellikleri vardır. Bilinen toksinler ve ağır metaller içeren musluk suyu yerine arıtılmış veya filtrelenmiş su içiniz. Damıtılmış su asittir, kaçınılmalıdır.
12) Et proteininin sindirimi zordur ve çok sindirim enzimi ister. Bağırsaklarda duran sindirilmemiş et çürür ve daha çok toksin birikimine neden olur.
13) Kanser hücrelerinin duvarları sert protein ile kaplıdır. Et yemekten kaçınarak veya azaltarak, kanser hücrelerinin protein duvarlarına saldıran enzimler daha çok açığa çıkar ve vücudun öldürücü hücrelerinin kanser hücrelerini yok etmelerini sağlar.
14) Bazı destek maddeleri (IP6, Flor-ssence, Essiac, anti-oksidanlar, vitaminler, mineraller, EFA’lar v.s..) bağışıklık sistemini güçlendirerek, vücudun kendi öldürücü hücrelerinin kanser hücrelerini yok etmesine yardımcı olur. E vitamini gibi diğer destek maddelerinin de, vücudun hasarlı, istenmeyen veya ihtiyaç olmayan hücrelerin atılmasının normal yolu olan, apoptoziz veya programlanmış hücre ölümüne yardımcı olduğu bilinmektedir.
15) Kanser zihinsel, bedeni ve ruhsal bir hastalıktır. Öngörülü ve olumlu bir ruh kanser savaşçısını muzaffer yapar. Öfke, affetmezlik ve acı bedeni stresli ve asitli bir ortama sokar. Seven ve affeden bir ruha sahip olmayı öğrenin. Sakin olmayı ve hayatın tadını çıkarmayı öğrenin.
16) Kanser hücreleri oksijenli ortamda gelişemezler. Günlük egzersizler ve derin nefes alma hücre düzeyine kadar daha fazla oksijen alınmasına yardımcı olur. Oksijen terapisi kanser hücrelerini yok etmek için diğer bir yöntemdir.
JOHN HOPKINS HASTANESİ’NDEN KANSER GÜNCELLEMESİ
1) Mikrodalga fırına plastik kap koymayınız.
2) Dondurucuya su şişesi koymayınız.
3) Mikro dalga fırınına plastik ambalaj koymayınız.
4) John Hopkins Hastanesi bunu yakın bir zamanda bülteninde yayınlamıştır. Bu bilgi Walter Reed Ordu Tıp Merkezi tarafından da yayınlanmaktadı r. Dioksin kimyasalları kansere, özellikle de göğüs kanserine, neden olmaktadır. Dioksinler vücudumuzun hücreleri için son derece zehirlidir. Plastik şişelerdeki suyu dondurmayınız, çünkü bu plastiğin içindeki dioksinin salınmasına neden olur.
Castle Hastanesi Sağlıklılık Programı Yöneticisi Dr. Edward Fujimoto bu sağlık tehdidini anlatmak için yakınlarda bir televizyon programına çıktı. Dioksinleri ve bizim için ne kadar kötü olduklarını anlattı. Plastik kaplar içindeki yiyeceklerimizi mikrodalgaya koyarak ısıtma ve pişirmenin ne kadar vahim sonuçlara sebebiyet verdiğini anlattı.
Lütfen bu makaleyi hayatınızda sizin için önemli olan herkese gönderin.

Dr Edward Fujimoto is Real – The Cancer Update Emails Are Not

The Edward Fujimoto email is circulating again. This rumor lists an article about Dr. Edward Fujimoto saying that he appeared on a TV station in Huntsville, Alabama. The article is only available in Japanese, but the ‘doctor’ is on an American TV show. So have the article translated if it’s legit.

Dr. Edward Fujimoto
Dr. Edward Fujimoto

The Real Fujimoto

Dr. Edward Fujimoto is real and was the Manager of the Wellness and Lifestyle Medicine Department at Castle Medical Center in Hawaii. The fake email is the result of an interview he did on KHON-TV channel 2 in Hawaii on January 23, 2002.

Edward Fujimoto

Director of Medical Affairs at Green Panel Corporation Austin, Texas -Present Position

Past Employment

  1. Director of Research and Lifestyle Medicine at New Hope Medical Center
  2. Professor at Loma Linda University School of Public Health
  3. Adjunct Professor at Fukushima Prefectural School of Public Health
  4. Manager of Wellness and Lifestyle Medicine Center at Castle Medical Center
  5. Preventionist and Director of Healthy Vacations at Guam SDA Clinic
  6. Adjunct Professor at Saniku College
  7. Director of Health Promotion Center at Tokyo Adventist Hospital
  8. Supervisory Mechanical Engineer at U.S. Naval Ships System Command, Mare Island Naval Shipyard, California
  9. Nuclear Submarine Project Design Engineer at U.S. Naval Ships System Command, Mare Island Naval Shipyard, California.

 

Johns Hopkins Hospital

Johns Hopkins Hospital
Walter Reed Army Medical Center - 1919

Walter Reed Army Medical Center – 1919

Cancer Update from Johns Hopkins – Fake

Every so often a new version of this email arrives in your inbox. It’s always circulated by a well meaning person aiming to help you prevent cancer. It looks so genuine because it uses world famous medical centers like Johns Hopkins and Walter Reed Army Medical Center. With a little investigation, you’d find out that neither one of these medical centers induce the email.

The email has become a immense problem, that the National Cancer Institute, American Cancer Society, and the Johns Hopkins Kimmel Cancer Center have placed words of warning on their web sites. Emails offering uncomplicated remedies for circumventing and curing cancer are the latest web-influenced movement. To achieve integrity, the anonymous authors misleadingly attribute their work to esteemed research institutions like Johns Hopkins. This is the case with the so-called“Cancer Update from Johns Hopkins.” As a matter of fact,Johns Hopkins wrote a disclaimer and showed evidence why the email is a myth. Here’s a copy of the latest version of that email:

AFTER YEARS OF TELLING PEOPLE CHEMOTHERAPY IS THE ONLY WAY TO TRY (‘TRY’),
BEING THE KEY WORD) TO ELIMINATE CANCER, JOHNS HOPKINS IS FINALLY STARTING
TO TELL YOU THERE IS AN EFFECTIVE ALTERNATIVE WAY…

Cancer Update from Johns Hopkins:

1. Every person has cancer cells in the body. These cancer cells do not show
up in the standard tests until they have multiplied to a few billion. When
doctors tell cancer patients that there are no more cancer cells in their
bodies after treatment, it just means the tests are unable to detect the
cancer cells because they have not reached the detectable size.

2. Cancer cells occur between 6 to more than 10 times in a person’s
lifetime.

3 When the person’s immune system is strong the cancer cells will be
destroyed and prevented from multiplying and forming tumors.

4. When a person has cancer it indicates the person has multiple nutritional
deficiencies. These could be due to genetic, environmental, food and
lifestyle factors.

5. To overcome the multiple nutritional deficiencies, changing diet and
including supplements will strengthen the immune system.

6. Chemotherapy involves poisoning the rapidly-growing cancer cells and also
destroys rapidly-growing healthy cells in the bone marrow, gastrointestinal
tract etc, and can cause organ damage, like liver, kidneys, heart, lungs
etc.

7. Radiation while destroying cancer cells also burns, scars and damages
healthy cells, tissues and organs.

8. Initial treatment with chemotherapy and radiation will often reduce tumor
size. However prolonged use of chemotherapy and radiation do not result in
more tumor destruction.

9. When the body has too much toxic burden from chemotherapy and radiation
the immune system is either compromised or destroyed, hence the person can
succumb to various kinds of infections and complications..

10. Chemotherapy and radiation can cause cancer cells to mutate and become
resistant and difficult to destroy. Surgery can also cause cancer cells to
spread to other sites.

11. An effective way to battle cancer is to starve the cancer cells by not
feeding it with the foods it needs to multiply..

*CANCER CELLS FEED ON:

a. Sugar is a cancer-feeder. By cutting off sugar it cuts off one important
food supply to the cancer cells. Sugar substitutes like NutraSweet, Equal,
Spoonful, etc are made with Aspartame and it is harmful. ALL DIET CARBONATED
DRINKS CONTAIN ASPARTAME AND ARE POISONOUS. A better natural substitute
would be Manuka honey or molasses, but only in very small amounts. Table
salt has a chemical added to make it white in color. Better alternative is
Bragg’s aminos or sea salt.

b. Milk causes the body to produce mucus, especially in the
gastro-intestinal tract. Cancer feeds on mucus. By cutting off milk and
substituting with unsweetened soy milk cancer cells are being starved.

c. Cancer cells thrive in an acid environment. A meat-based diet is acidic
and it is best to eat fish, and a little chicken rather than beef or pork.
Meat also contains livestock antibiotics, growth hormones and parasites,
which are all harmful, especially to people with cancer.

d. A diet made of 80% fresh vegetables and juice, whole grains, seeds, nuts
and a little fruits help put the body into an alkaline environment. About
20% can be from cooked food including beans. Fresh vegetable juices provide
live enzymes that are easily absorbed and reach down to cellular levels
within 15 minutes to nourish and enhance growth of healthy cells. To obtain
live enzymes for building healthy cells try and drink fresh vegetable juice
(most vegetables including bean sprouts) and eat some raw vegetables 2 or 3
times a day. Enzymes are destroyed at temperatures of 104 degrees F (40
degrees C).

e. Avoid coffee, tea, and chocolate, which have high caffeine. Green tea is
a better alternative and has cancer fighting properties. Water – best to
drink purified water, or filtered, to avoid known toxins and heavy metals in
tap water. Distilled water is acidic, avoid it.

12.. Meat protein is difficult to digest and requires a lot of digestive
enzymes. Undigested meat, especially pork, remaining in the intestines
becomes putrefied and leads to more toxic buildup.

13. Cancer cell walls have a tough protein covering. By refraining from or
eating less meat it frees more enzymes to attack the protein walls of cancer
cells and allows the body’s killer cells to destroy the cancer cells.

14. Some supplements build up the immune system (IP6, Flor-ssence, Essiac,
anti-oxidants, vitamins, minerals, EFAs etc.) to enable the bodies own
killer cells to destroy cancer cells.. Other supplements like vitamin E are
known to cause apoptosis, or programmed cell death, the body’s normal method
of disposing of damaged, unwanted, or unneeded cells.

15. Cancer is a disease of the mind, body, and spirit. A proactive and
positive spirit will help the cancer warrior be a survivor. Anger,
un-forgiveness and bitterness put the body into a stressful and acidic
environment. Learn to have a loving and forgiving spirit. Learn to relax and
enjoy life.

16. Cancer cells cannot thrive in an oxygenated environment. Exercising
daily, and deep breathing help to get more oxygen down to the cellular
level. Oxygen therapy is another means employed to destroy cancer cells.

1. No plastic containers in micro.

2. No water bottles in freezer.

3. No plastic wrap in microwave.

Johns Hopkins has recently sent this out in its newsletters. This
information is being circulated at Walter Reed Army Medical Center as well.
Dioxin chemicals cause cancer, especially breast cancer. Dioxins are highly
poisonous to the cells of our bodies. Don’t freeze your plastic bottles with
water in them as this releases dioxins from the plastic. Recently, Dr.
Edward Fujimoto, Wellness Program Manager at Cast le Hospital, was on a TV
program to explain this health hazard. He talked about dioxins and how bad
they are for us. He said that we should not be heating our food in the
microwave using plastic containers. This especially applies to foods that
contain fat. He said that the combination of fat, high heat, and plastics
releases dioxin into the food and ultimately into the cells of the body.
Instead, he recommends using glass, such as Corning Ware, Pyrex or ceramic
containers for heating food. You get the same results, only without the
dioxin. So such things as TV dinners, instant ramen and soups, etc., should
be removed from the container and heated in something else. Paper isn’t bad
but you don’t know what is in the paper. It’s just safer to use tempered
glass, Corning Ware, etc. He reminded us that a while ago some of the fast
food restaurants moved away from the foam containers to paper. The dioxin
problem is one of the reasons.

Also, he pointed out that plastic wrap, such as Saran, is just as dangerous
when placed over foods to be cooked in the microwave. As the food is nuked,
the high heat causes poisonous toxins to actually melt out of the plastic
wrap and drip into the food. Cover food with a paper towel instead.

Chest x-ray showing lung cancer in the left lung

Chest x-ray showing lung cancer in the left lung
Malignant Mesothelioma, coronal CT scan.  Legend: the malignant mesothelioma is indicated by yellow arrows, the central pleural effusion is marked with a yellow star. (1) right lung, (2) spine, (3) left lung, (4) ribs, (5) aorta, (6) spleen, (7) left

Malignant Mesothelioma, coronal CT scan. Legend: the malignant mesothelioma is indicated by yellow arrows, the central pleural effusion is marked with a yellow star. (1) right lung, (2) spine, (3) left lung, (4) ribs, (5) aorta, (6) spleen, (7) left

Answering the Hoax

Johns Hopkins Kimmel Cancer Center website makes this statement:

STATEMENT: EMAIL HOAX REGARDING CANCER

Information falsely attributed to Johns Hopkins called, “CANCER UPDATE FROM JOHN HOPKINS” describes properties of cancer cells and suggests ways of preventing cancer. Johns Hopkins did not publish the information, which often is an email attachment, nor do we endorse its contents. The email also contains an incorrect spelling of our institution as “John” Hopkins; whereas, the correct spelling is “Johns” Hopkins. For more information about cancer, please read the information on our web site or visit the National Cancer Institute’s web site at www.cancer.gov. Please help combat the spread of this hoax by letting others know of this statement.

The individual(s) who created this email have kept it current by correcting the misspelling “John Hopkins” as you can note in the copy of the email. This would indicate the person is intentionally passing on erroneous information in the hopes the email will continue to be forwarded.

Johns Hopkins Kimmel Cancer Center experts goes through each statement in the email hoax and provide real responses. A sample of the Email hoax contentions #1 and 2: Everyone Has Cancer Cells

Cancer is a genetic disease resultant from a selection of mutations and alterations either inherited from our parents or, more commonly, acquired over time due to environmental contact and behaviors, such as smoking and poor diet. These modification turn off important cell growth regulators allowing cells to repeatedly divide unchecked, explains Luis Diaz, a clinician-scientist in Ludwig Center for Cancer Genetics. This type of cell is called a malignant or cancer cell. Among the trillions of cells in the human body, unavoidably everyone has some abnormal or atypical cells that acquire some of the characteristics of cancer cells, most resolve themselves and never result in cancer, says Diaz.

There is no single or standard test for cancer. There are ways to screen for certain cancers with tests such as colonoscopy for colon cancer, mammography for breast cancer, PSA for prostate cancer, and the Pap smear for cervical cancer, and these tests can detect cancers in a very early and curable stage. For many cancers, there presently are no screening tests, and they are diagnosed when they begin to cause symptoms.

Diaz and other Kimmel Cancer Center researchers are working on new tests that detect abnormal DNA discard by cancer cells into blood and body fluids and have the capability to find cancers before they cause any symptoms. Advances like this could lead to a broad-based screening test for cancer.

Tests like these also are used to identify cancer recurrences and malignant cells left behind following surgery, and can find cancers that are not detectable under the microscope or in x-rays.

Other investigators are studying cancer stem cells. They are stealth cells that make up just a tiny fraction of a tumor. While small in number, researchers consider they may be the cells that drive certain cancers and lead to cancer recurrence. Therapies that aim at these cells are now being tested in clinical trials.

A team of our breast cancer researchers developed a technique that could make it possible to detect breast cancer from the DNA contained in a single drop of blood.

But, while evasive cancer cells are a challenge and the focus of ongoing research, it does not mean, as the email contends, that all patients, even those treated successfully for cancer, have cancers-in-waiting—undetectable but still there. People are treated and completely cured of cancer every day.

Read the rest of Johns Hopkins responses by clicking here.

Sheryl Crow

Sheryl Crow
Some usual objects made of various kinds of plastic

Some usual objects made of various kinds of plastic
microwave

microwave

Other Hoax

The updated version of the email has now combined misinformation on another hoax email that has been circulating since 2004 regarding plastic containers, bottles, wrap claiming that heat releases dioxins which cause cancer also was not published by Johns Hopkins.  The creator of the email has been clever enough to keep the email updated and rewritten to keep pace with those that expose the myth.

Johns Hopkins Bloomberg School of Public Healthreleased January 15, 2008, Email Hoax Regarding Freezing Water Bottles and Microwave Cooking. The site includes the disclaimer:These messages, frequently titled “Johns Hopkins Cancer News” or “Johns Hopkins Cancer Update,” are falsely attributed to Johns Hopkins and we do not endorse their content.  The site contains corrected information such, “Freezing water does not cause the release of chemicals from plastic bottles.”

The subsequent version tells the story of a seventh-grade student who decided to do some experiments with microwave radiation on food wrapped in plastic. She is said to have enlisted the help of the National Center for “Toxicological” Research in Arkansas.  The student allegedly found that not only is there carcinogens migrating from the plastic into food during microwaving, but other substances as well.  Again using a verifiable institution, The National Center for Toxicological Research (NCTR), FDA’s internationally recognized research center, gives creditably to the email. Who wouldn’t trust a fore thinking seventh grader?

Another report declares that singer Sheryl Crow, who is suffering from breast cancer, got her cancer from drinking from plastic water bottles left in the sun. Supposedly the plastic bottle got too hot and, as a result, was contaminated with dioxins.

CancerYou’re Responsible for Your Health Information

The next time you get an unsolicited e-mail containing some kind of health or safety scare, first check several of these debunking websites before you pass it on to everyone on your email list. Go to the company, facility and/or medical center web site quoted in the email to see if they published a disclaimer. You are responsible for your medical care and that includes the information you accept.

See links for more information.

Link Resources

A Doctor’s Posthumous Vindication

By HARVEY SILVERGLATE

Peter Gleason was a psychiatrist who devoted much of his professional life to caring for what government officials call “underserved populations.” He would have been thrilled to learn that on Dec. 3 in New York, a three-judge panel of the U.S. Court of Appeals for the Second Circuit issued a ringing opinion that vindicated the conduct for which he was indicted and arrested in 2006.

Unfortunately, Gleason did not live to see this welcome reversal of the federal government’s crusade against him and the promotion of Xyrem—a drug widely used by physicians, including Gleason, to treat a number of medical conditions beyond what the federal Food and Drug Administration approved it for. Hounded for years, he saw his career and finances ruined by the relentless war waged against him by FDA bureaucrats and Justice Department prosecutors. Gleason committed suicide on Feb. 7, 2011.

The doctor’s troubles stemmed from lectures he gave attesting to the efficacy of Xyrem, a pharmaceutical originally developed for use in narcolepsy but found by physicians to be effective against a number of conditions, including fibromyalgia and chronic fatigue syndrome. The FDA had not given formal approval for these so-called “off-label” uses since the manufacturer had not submitted an application covering those ailments.

Obtaining FDA approval for a new drug is time-consuming and expensive. Once a drug is approved for a certain use (which its FDA-approved “label” describes), physicians often discover, through use of the drug as well as through further research and field experience, other conditions for which the drug is a safe and effective remedy. Manufacturers rarely go through the FDA approval process for such additional uses of already-approved drugs due to the expense. FDA regulations forbid them to promote these “off-label” uses.

Yet such uses are widely practiced by experienced physicians. They know, for instance, that Neurontin, approved to treat seizures, can also relieve neuropathic, or nerve, pain. Avastin, approved to limit new blood-vessel growth in tumors, ameliorates age-related muscular degeneration. Aspirin is widely deemed a miracle drug because of its uses beyond pain relief, largely discovered by trial and error.

Unlike manufacturers, physicians are not restricted by federal law from prescribing an FDA-approved drug for an off-label condition. They are perfectly free to communicate the results of their experience to fellow physicians, or to publish in medical journals. Such communications have long been recognized to be protected by the physicians’ professional prerogatives and free-speech rights.

So how was it that Gleason was indicted on a conspiracy charge of communicating to his fellow physicians that he found Xyrem effective for off-label medical conditions such as chronic pain and bipolar disorder? Gleason, it turns out, often revealed his experiences with Xyrem to audiences of physicians during paid appearances at events sponsored by its maker, Orphan Medical—a common practice within the medical community. The prosecutors’ convoluted legal theory was that even if Gleason himself was free to recommend Xyrem, he had lost his First Amendment right to communicate his medical knowledge because he had become an agent of sorts for the manufacturer and “conspired” with employees of the company, who had to stick to promoting only FDA-approved uses.

No wonder Gleason was shocked when he found himself surrounded and handcuffed by six federal agents who were waiting for him at a train station on New York’s Long Island on March 6, 2006. When prosecutors could not convince Gleason to cooperate against the drug manufacturer—he did not feel that either he or Orphan Medical had violated the law—they indicted him, triggering a downward spiral that wreaked havoc on his medical practice.

Gleason was not a wealthy man, but whatever assets he had accumulated during his working life were placed in limbo when the feds included in the indictment a “criminal forfeiture allegation.” This sought to force him to turn over to the government “any property, real and personal, that constitutes or is derived, directly or indirectly, from gross proceeds traceable to the commission of offenses.” Virtually all of Gleason’s income and assets were derived from his medical practice. Thus prevented from hiring private counsel of his choice, he required free legal representation from the Federal Defenders Service, tasked with representing indigent defendants.

The ordeal of fighting a federal indictment, a daunting process even for the wealthy, exhausted Gleason, with whom I corresponded when I included his case in a book I was writing about how federal bureaucrats and prosecutors go after innocent defendants for innocuous behavior. He grew increasingly dispirited and finally decided to accept an offer that he felt he could not refuse. He pleaded guilty to a misdemeanor alleging his conspiracy with Orphan Medical and was sentenced to one year of probation and a $25 fine.

But Gleason’s career was ruined and his pride decimated. He had difficulty holding a hospital or clinic job, and his medical license was placed into question. He was despondent the last time I spoke with him, and he subsequently took his life by hanging himself.

Just under two years later, Gleason’s posthumous vindication was achieved by his co-defendant, Alfred Caronia, a sales representative for Xyrem’s manufacturer, Orphan Medical (later acquired by Jazz Pharmaceuticals JAZZ -0.21% ), who had refused to make a deal with the feds. With the aid of aggressive legal counsel and the “friend-of-the-court” backing of two public-interest organizations, Mr. Caronia won the point that Gleason had many times argued to anyone who would listen: The First Amendment protects the right of physicians, drug manufacturers, sales representatives and anyone else who wishes to convey truthful, factual information about the beneficial uses of drugs in the relief of illness and pain.

What the appeals court affirmed in ruling for the defendants on Dec. 3 seems so obvious now. But it’s too late for Peter Gleason. And too late for the feds to apologize, if they were so inclined.

Mr. Silverglate, a Boston lawyer, is the author of “Three Felonies a Day: How the Feds Target the Innocent” (Encounter Books, 2009).

A version of this article appeared Dec. 26, 2012, on page A13 in some U.S. editions of The Wall Street Journal, with the headline: A Doctor’s Posthumous Vindication.

BAD MEDICINE

Fake pharmaceuticals

Bad medicine

The world’s drug supply is global. Governments have failed to keep up

Oct 13th 2012 | ABUJA AND WASHINGTON, DC | from the print edition

 

 

PATIENTS expect drugs to be safe. But even in supposedly well-run health systems, they can be useless—or deadly. Tainted steroids from a compounding pharmacy (one which mixes its own drugs) near Boston had killed 11 people with fungal meningitis and sickened more than 100 as of October 10th. A contaminated blood thinner, heparin, was linked to 149 American deaths in 2007-08. This year it emerged that some vials of the cancer medicine Avastin contained no active ingredient.

No one knows exactly what share of medicines are fake, ill-made, stolen or diverted. But bad pharma is a global problem, which national drug-safety agencies are struggling to contain. It particularly afflicts countries where officials are bribable, health systems lax and consumers desperate. In Nigeria, Africa’s largest market for medicines, a survey by the World Health Organisation (WHO) in 2011 found that 64% of antimalarial drugs were fake. Over 70% of drugs consumed in Nigeria are imported from India and China, widely seen as the biggest source of fakes. Paul Orhii, of Nigeria’s drug agency, blames “a shambolic system and porous borders”.

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Salesmen have peddled worthless cures for millennia. But the 21st century is turning into a golden age for bad drugs. In Boston, the fungal meningitis spread because of poor oversight. Price pressure encourages even well-intentioned drugmakers to cut corners. For criminals, fake pharma is lucrative and the penalties are usually low. Indeed, the drug supply-chain is a cheat’s paradise.

Raw materials come from one place and are processed into active ingredients in another. Pill-fillers and coating come from other sources. Manufacturing and packaging may be separate. To reach the dispensary, the drug passes through distribution chains (and may be repackaged). In America 80% of drugs’ active ingredients come from abroad (drug imports there more than doubled from 2002 to 2010, accounting for 40% of finished medicine).

This creates a regulatory nightmare. In the heparin case Chinese suppliers replaced the main ingredient with a cheaper, dangerous substance that still passed authentication tests. The fake Avastin apparently hopped from Turkey to Britain to America, with help from a Canadian online pharmacy. Do-gooding attempts may backfire, too. The WHO has a “prequalification” scheme that authorises cheap, good drugs for aid programmes. But Roger Bate of the American Enterprise Institute, in a paper published in July, found that 7% of such drugs in his sample failed.

Attempts abound to stem the scourge. The latest raids in Operation Pangea (an international police campaign against illegal online pharmacies) involved 100 countries and shut down more than 18,000 online pill-pushers. But such pharmacies are not necessarily the villains: they often sell real drugs (at low prices); and many fakes are on sale from reputable offline outlets.

Some poor countries think that rich ones simply want an excuse to bust their generic drug industries. Rows about the definition of “counterfeit” have crippled the WHO’s International Medical Products Anti-Counterfeiting Taskforce, or IMPACT, launched in 2006. Now new working groups are mulling the meaning of SFFC (“spurious/falsely-labelled/falsified/counterfeit”) drugs. It may add another “S” for “substandard”. Pirates are not trembling.

Most other international efforts are moving slowly, says Mr Bate, author of a book called “Phake”. To punish counterfeiters more harshly and speed information-sharing, 18 European countries signed the Medicrime convention in 2011. But only Ukraine has ratified it. The G8 group of rich countries published a wordy declaration in May, but has done little since.

For years governments and companies have talked about “track-and-trace” systems to identify and authenticate medicines. Though the technology exists, countries cannot agree what to use. Different firms hawk their own schemes; regulators disagree about what should be tracked.

My pills, not yours

So individual states are taking their own steps. Nigeria has spearheaded an impressive counterattack, which by some counts has brought the share of fake medicines down from around half to a tenth in five years. One means is TruScan, a cheap hand-held spectroscope that allows officials to spot fakes at the point of import (America, Germany, Sweden and Canada now use this, too). Nigeria has also deployed a scratch-off label system, in which users text the revealed code from their phones to verify the product before consuming it. But the scheme is voluntary and so far only a few firms are using it.

China, concerned for the reputation of its drug-export trade, has staged big seizures of fakes (detaining nearly 2,000 people in August). It executed its top drug official in 2007 for approving untested medicine in exchange for bribes. India has commissioned feasibility studies of track-and-trace technology from Wipro, a software and services giant. The government talks of better manufacturing standards, but exhortation has yet to lead to action.

America’s Food and Drug Administration (FDA), the world’s biggest drug-safety agency, has steadily reached beyond the country’s borders. Since 2008 it has opened offices in China, India, South Africa, Jordan, Mexico, Belgium and other countries. A recent law sets higher penalties for counterfeiters and allocates money for the agency to inspect more factories overseas. But even the FDA admits it cannot police the world’s drug supply alone.

Drug firms often make better enforcement partners than governments do. John Clark, security chief for Pfizer, a pharma giant that makes Viagra, likes to tell a story about a man caught selling fakes who asked an undercover agent first if he was with “the Feds”, then whether he worked for Pfizer. His firm employs former police, investigators and customs officials all over the world. Usually it builds about 80% of a case, then hands it to local law-enforcers.

Yet, as officials fiddle, the problem grows. In January 2009, 81 countries noted counterfeit versions of 20 Pfizer drugs. As of July 2012, 106 had found 60 such fakes. “Counterfeiting is like a balloon filled with water,” says Nigeria’s Mr Orhii. “You push it on one side but when you remove your hand, it bounces back even stronger.”

Dr. Liston: Fastest surgeon

Before anesthesia, speed was essential to minimizing pain and improving odds of survival.

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Imagine lying on a table in a old-school operating room. Faces stare down at you from the viewing galleries above, and your leg throbs with pain from a broken bone — infection is just starting to set in. The door opens and three men in blood-stiffened aprons walk in, carting a collection of knives and saws. Two of them grab your shoulders and arms and pin you to the table. The third picks out one of the knives from the cart.

“Time me, gentlemen,” he calls out to the gathered spectators. “Time me.”

The man grabs your leg and begins to cut just below the knee. He continues to hold onto your leg as one of his lackeys gets a tourniquet around it. To free his cutting hand, he clasps the bloody knife in his teeth and picks up a saw. He cuts back and forth through the bone, drops the severed leg into a bucket filled with sawdust, and sews you up, to the applause of the men sitting in the wings. As promised they’ve timed the whole procedure — from first incision to clipping the loose threads on the sutures — at just two and a half minutes.

The man who just flew through your amputation with apparent reckless abandon was Dr. Robert Liston, one of the finest surgeons of the time.

Dr. Richard Gordon, a surgeon and medical historian, calls Liston the “fastest knife in the West End.” His style may have seemed careless, but in the age before anesthesia, speed was essential to minimizing the patient’s pain and improving their odds of surviving surgery. Slower surgeons sometimes had pain-wracked and panicked patients wrestle free from their assistants and flee from the operating room. Only about one of every 10 of Liston’s patients died on his operating table at London’s University College Hospital. The surgeons at nearby St. Bartholomew’s, meanwhile, lost about one in every four.

Liston’s quick hands were so sought after that patients sometimes had to camp out in his waiting room for days waiting for their turn to see him. Liston tried to see every last one of these patients, no matter their condition. He especially loved treating those cases that his fellow surgeons had dismissed as beyond help, which earned him a reputation among colleagues as being showy.

Occasionally, Liston’s speed and showmanship actually were a hindrance to his operations. Once, he took a patient’s testicles off along with the leg that was being amputated. His most famous (and possibly apocryphal) mishap was the operation where he was moving so fast that he took off a surgical assistant’s fingers as he cut through a leg and, while switching instruments, slashed a spectator’s coat. The patient and the assistant both died from infections of their wounds, and the spectator was so scared that he’d been stabbed that he died of shock. The fiasco is said to be the only known surgery in history with a 300 percent mortality rate.

Liston had more going for him than just a quick and (mostly) steady slice, though. He was a highly-regarded surgical instructor and prolific inventor. Some of his creations, like the “Liston splint” and “bulldog” locking forceps, are still around today. He also published two medical texts, The Elements of Surgery and Practical Surgery.

Towards the end of his career, Liston made medical history and performed a surgery that made his nimble hands obsolete in Britain. From that point on, pain would no longer be a hurdle to successful surgery, and speed wouldn’t be the surgeon’s greatest asset.

In 1846, Liston received a patient named Frederick Churchill, whose right knee had been causing him terrible problems for years. None of the treatments he’d been given before had worked, and now the only option was amputation. The day of the surgery, Liston walked into the operating room and, instead of grabbing a knife and asking his audience to time him, he pulled out a jar. Ether, American dentists and doctors had recently demonstrated, could be used as a surgical anesthetic. “We are going to try a Yankee dodge today, gentlemen,” Liston told the crowd, “for making men insensible.”

Liston’s colleague, Dr. William Squire, administered the anesthesia. He held a rubber tube to Churchill’s mouth so he could inhale the ether, and after a few minutes, he was out. Squire placed a handkerchief laced with more of the stuff over Churchill’s face to keep him that way, and then Liston began the operation.

A mere 25 seconds later, the amputation was complete. Churchill roused a few minutes later and reportedly asked when the operation was going to begin, to the amusement of the audience.

Further use of ether in Europe’s operating rooms revealed its drawbacks. It irritated surgeons’ lungs, caused vomiting and other side effects in patients and, in some windowless rooms where surgery was performed by gaslight, ignited and caused fires. Anesthetics would continue to improve and become more common in medicine, but Liston wouldn’t get to see much of their progress. He died in a sailing accident less than a year after Churchill’s surgery, still the fastest knife London had ever known.


This post originally appeared on Mental Floss, anAtlantic partner site.